"Establishment and validation of an in vitro cytotoxicity assess
「"Establishment and validation of an in vitro cytotoxicity assess」於資料集「EPQSummary_EnvironmentalMonitoringAndTesting」由單位「行政院環境保護署」的陳先生所提供，聯繫電話是02-2311-7722#2386，最近更新時間為：2023-07-30 01:01:45。 欄位Project Title的內容是"Establishment and validation of an in vitro cytotoxicity assessment of nanoparticle exposure" ， 欄位Project Subject的內容是"Nanomaterials have received considerable recent attention because of their unique properties and diverse applications in technology and life sciences. However, the nano-structures of these materials possess very different physical and chemical properties compared to their larger size counterparts. Given the increasing use of nanoparticles in a range of products, it has become crucial to develop a fundamental understanding of the biological effects of nanoparticle exposure. Many in vitro studies have suggested that nanoparticles are cytotoxic and genotoxic; however, results are inconsistent, mainly due to interference between nanoparticles and dye molecules commonly used in traditional cytotoxicity assays. The purpose of this study was to establish and validate an in vitro cytotoxicity screening platform for evaluating biological effects of nanoscale zero-valent iron. In addition, the characterization of nanoparticles will be examined by TEM/SEM. Moreover, the effect of PM2.5 particles, fine particles 2.5 micrometers or less in size will be examined using the cell impedance measurement and flow cytometry. " ， 欄位Project Year的內容是2014 ， 欄位Organizer的內容是"Environmental Analysis Laboratory" ， 欄位Executive Unit的內容是"國立中興大學" ， 欄位Reporting download URL的內容是https://epq.epa.gov.tw/project/filedownload.aspx?fid=73792 ， 欄位Publish Date的內容是20150201 。
Project Title
"Establishment and validation of an in vitro cytotoxicity assessment of nanoparticle exposure"
Project Subject
"Nanomaterials have received considerable recent attention because of their unique properties and diverse applications in technology and life sciences. However, the nano-structures of these materials possess very different physical and chemical properties compared to their larger size counterparts. Given the increasing use of nanoparticles in a range of products, it has become crucial to develop a fundamental understanding of the biological effects of nanoparticle exposure. Many in vitro studies have suggested that nanoparticles are cytotoxic and genotoxic; however, results are inconsistent, mainly due to interference between nanoparticles and dye molecules commonly used in traditional cytotoxicity assays. The purpose of this study was to establish and validate an in vitro cytotoxicity screening platform for evaluating biological effects of nanoscale zero-valent iron. In addition, the characterization of nanoparticles will be examined by TEM/SEM. Moreover, the effect of PM2.5 particles, fine particles 2.5 micrometers or less in size will be examined using the cell impedance measurement and flow cytometry. "
Project Year
2014
Organizer
"Environmental Analysis Laboratory"
Executive Unit
"國立中興大學"
Reporting download URL
Publish Date
20150201
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