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"Establishment and validation of an in vitro cytotoxicity assess

"Establishment and validation of an in vitro cytotoxicity assess」於資料集「EPQSummary_EnvironmentalMonitoringAndTesting」由單位「行政院環境保護署」的陳先生所提供,聯繫電話是02-2311-7722#2386,最近更新時間為:2023-07-30 01:01:45。 欄位Project Title的內容是"Establishment and validation of an in vitro cytotoxicity assessment of nanoparticle exposure in envi" , 欄位Project Subject的內容是"Nanomaterials have received considerable recent attention because of their unique properties and diverse applications in technology and life sciences. However, the nano-structures of these materials possess very different physical and chemical properties compared to their larger size counterparts. Given the increasing use of nanoparticles in a range of products, it has become crucial to develop a fundamental understanding of the biological effects of nanoparticle exposure. For the past years, we have established an in vitro cytotoxicity screening platform measuring cell impedance. Due to the increased concentrations of PM2.5 in air and accumulating evidences suggesting of their adverse effects in human through airway, it is important and of interesting to evaluate the potential biological adverse effects of PM2.5 collected from air samples in different area. Several factors, such as their effects on cell growth, ROS generation, and cell apoptosis are evaluated. In addition, the biological effects of nanoparticles used for environmental remediation will also be analyzed. Our results have suggested that synthesized schwertmannite (SHM) nanomaterials are bio-compatible and not significantly toxic to mammalian cells, implying they could be reliably be used in environment remediation." , 欄位Project Year的內容是2015 , 欄位Organizer的內容是"Environmental Analysis Laboratory" , 欄位Executive Unit的內容是"國立中興大學" , 欄位Reporting download URL的內容是https://epq.epa.gov.tw/project/filedownload.aspx?fid=181393 , 欄位Publish Date的內容是20181225

Project Title

"Establishment and validation of an in vitro cytotoxicity assessment of nanoparticle exposure in envi"

Project Subject

"Nanomaterials have received considerable recent attention because of their unique properties and diverse applications in technology and life sciences. However, the nano-structures of these materials possess very different physical and chemical properties compared to their larger size counterparts. Given the increasing use of nanoparticles in a range of products, it has become crucial to develop a fundamental understanding of the biological effects of nanoparticle exposure. For the past years, we have established an in vitro cytotoxicity screening platform measuring cell impedance. Due to the increased concentrations of PM2.5 in air and accumulating evidences suggesting of their adverse effects in human through airway, it is important and of interesting to evaluate the potential biological adverse effects of PM2.5 collected from air samples in different area. Several factors, such as their effects on cell growth, ROS generation, and cell apoptosis are evaluated. In addition, the biological effects of nanoparticles used for environmental remediation will also be analyzed. Our results have suggested that synthesized schwertmannite (SHM) nanomaterials are bio-compatible and not significantly toxic to mammalian cells, implying they could be reliably be used in environment remediation."

Project Year

2015

Organizer

"Environmental Analysis Laboratory"

Executive Unit

"國立中興大學"

Publish Date

20181225

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