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Project for risk evaluation and management of chemical substances

Project for risk evaluation and management of chemical substances」於資料集「EPQSummary_ChemicalSubstanceManagement」由單位「行政院環境保護署」的陳先生所提供,聯繫電話是02-2311-7722#2386,最近更新時間為:2023-07-30 01:01:48。 欄位Project Title的內容是Project for risk evaluation and management of chemical substances , 欄位Project Subject的內容是This project has collected the data of chemical substance assessment standard announced by European Union, the United States, and Japan, including the list of relevant assessment cases. After relevant data was collected, this project has analyzed the assessment cases about N-Methylpyrrolidinone(NMP)and Antimony Trioxide(ATO)from US EPA, and the assessment cases about Naphthalene from European Chemicals Agency. To research the development and status of risk assessment for chemical substances in Taiwan, this project has analyzed the regulations, operation procedures, historical investigation and assessment cases, and parameters investigation data from Environmental Protection Administration, Ministry of Health and Welfare, Ministry of Labor, Council of Agriculture, and Ministry of Economic Affairs in Taiwan for the estimation of resource integration and feasibility research in the future. After the research, the results and data were summarized as the reference for planning the chemical substance risk assessment operation procedures. As for the methods for the chemical substance risk assessment, this project has researched the details from quantitative structure-activity relationships Toolbox(QSAR Toolbox)and European Union System for the Evaluation of Substances(EUSES)model developed by European Chemicals Agency, and also the details from Ecological Structure Activity Relationships(ECOSAR), Estimation Programs Interface Suite (EPI Suite)and Exposure and Fate Assessment Screening Tool(E-FAST) model developed by US EPA. By applying the controlled chemical substances in Taiwan such as Bisphenol A(BPA)and Dimethyl Fumarate(DMFu)as the samples for testing each mode, this project has also proposed suggestions in accordance with the testing results for Taiwan to precede these modes. With NMP and 1-Bromopropane(1-BP)as testing substances, this project has selected some aquatic creatures such as Chlorella vulgaris, Daphnia magna, and Cyprinus carpio for testing the collected ecological risk examination methods from domestic and abroad. A trial calculation for the Predicted no-effect concentration (PNEC) for making a chemical substance ecological risk assessment has been made according to the testing results, which could be as the reference parameters for the relevant assessment works in the future. For the database planning of chemical substance risk assessment parameters, this project has firstly summarized and categorized all necessary items for chemical substance risk assessment. Second, this project has collected the database which government of Taiwan and other countries have built for chemical substance risk assessment. After the above process, this project has proposed an initial model for the database of chemical substance risk assessment in Taiwan. Integrating the works and results mentioned above with professional suggestion from twice profession consultation conference, this project has eventually summarized the suggestions for the policy and regulation establishment in Taiwan about chemical substance risk assessment, and the advice for medium- to long-term development in the future. , 欄位Project Year的內容是2019 , 欄位Organizer的內容是Toxic and Chemical Substances Bureau , 欄位Executive Unit的內容是瑞昶科技股份有限公司 , 欄位Reporting download URL的內容是https://epq.epa.gov.tw/ProjectDoc/FileDownload?fid=212741&proj_id=1080085565&doc_kind=1 , 欄位Publish Date的內容是20200122

Project Title

Project for risk evaluation and management of chemical substances

Project Subject

This project has collected the data of chemical substance assessment standard announced by European Union, the United States, and Japan, including the list of relevant assessment cases. After relevant data was collected, this project has analyzed the assessment cases about N-Methylpyrrolidinone(NMP)and Antimony Trioxide(ATO)from US EPA, and the assessment cases about Naphthalene from European Chemicals Agency. To research the development and status of risk assessment for chemical substances in Taiwan, this project has analyzed the regulations, operation procedures, historical investigation and assessment cases, and parameters investigation data from Environmental Protection Administration, Ministry of Health and Welfare, Ministry of Labor, Council of Agriculture, and Ministry of Economic Affairs in Taiwan for the estimation of resource integration and feasibility research in the future. After the research, the results and data were summarized as the reference for planning the chemical substance risk assessment operation procedures. As for the methods for the chemical substance risk assessment, this project has researched the details from quantitative structure-activity relationships Toolbox(QSAR Toolbox)and European Union System for the Evaluation of Substances(EUSES)model developed by European Chemicals Agency, and also the details from Ecological Structure Activity Relationships(ECOSAR), Estimation Programs Interface Suite (EPI Suite)and Exposure and Fate Assessment Screening Tool(E-FAST) model developed by US EPA. By applying the controlled chemical substances in Taiwan such as Bisphenol A(BPA)and Dimethyl Fumarate(DMFu)as the samples for testing each mode, this project has also proposed suggestions in accordance with the testing results for Taiwan to precede these modes. With NMP and 1-Bromopropane(1-BP)as testing substances, this project has selected some aquatic creatures such as Chlorella vulgaris, Daphnia magna, and Cyprinus carpio for testing the collected ecological risk examination methods from domestic and abroad. A trial calculation for the Predicted no-effect concentration (PNEC) for making a chemical substance ecological risk assessment has been made according to the testing results, which could be as the reference parameters for the relevant assessment works in the future. For the database planning of chemical substance risk assessment parameters, this project has firstly summarized and categorized all necessary items for chemical substance risk assessment. Second, this project has collected the database which government of Taiwan and other countries have built for chemical substance risk assessment. After the above process, this project has proposed an initial model for the database of chemical substance risk assessment in Taiwan. Integrating the works and results mentioned above with professional suggestion from twice profession consultation conference, this project has eventually summarized the suggestions for the policy and regulation establishment in Taiwan about chemical substance risk assessment, and the advice for medium- to long-term development in the future.

Project Year

2019

Organizer

Toxic and Chemical Substances Bureau

Executive Unit

瑞昶科技股份有限公司

Publish Date

20200122

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