The Development of Decision-making Tool for Chemical Management
「The Development of Decision-making Tool for Chemical Management 」於資料集「EPQSummary_ChemicalSubstanceManagement」由單位「行政院環境保護署」的陳先生所提供，聯繫電話是02-2311-7722#2386，最近更新時間為：2023-07-30 01:01:48。 欄位Project Title的內容是The Development of Decision-making Tool for Chemical Management Based on Risk Analysis: A Pilot Study ， 欄位Project Subject的內容是In recent years, several incidents of improper use of chemical substances have occurred in Taiwan, causing harm to the environment and the public. In order to more effectively control the source, in 2016, the Toxic and Chemical Substances Bureau of the Environmental Protection Administration of the Executive Yuan was established to strengthen the control, management and supervision of hazardous chemicals for the safeguard of people's health.
This project consolidates the classification and assessment frameworks of chemical substances in the European Union, the United States and Canada to discuss the risk-assessment-based classification methods of chemical substances, specifically focusing on their regulatory framework, evaluation and screening process, and use of tools and selection criteria. In addition, the current international trend of advancements in the process of chemical screening are also discussed. The management and evaluation of chemical substances has gradually begun to transform from evaluating single substances to a grouping approach where chemical substances are first classified into groups with similar characteristics, and then evaluating the same class of substances at the same time. Among the many classification schemes, classification based on the chemical’s mode of action is gradually being emphasized, not only for carcinogens, but also non-carcinogenic effects, endocrine effects and ecological assessments.
The risk assessment process relies heavily on relevant toxicological information, especially in the steps of hazard identification and dose-response assessment, which make use of data collected from animal experiments. Research has begun to establish methods for data quality assessments and the use of non-experimental toxicological data, including high-throughput screening, computational toxicology, in-silico methods, and integrated testing strategy in risk assessment in hope to replace traditional in-vitro and in-vivo approach.
Based on current international trends of chemical substance management framework, this project analyzes the definition of the class 4 toxic chemical substances and concerned chemical substances under the current regulatory framework. The feasibility of distinguishing the two classes of chemicals by their mode of action and human relevance is discussed. Recommendations are made for planning future development and applications of automated chemical screening tools based on existing data analysis tools and Quantitative Structure Activity Relationship (QSAR) models. For risk assessment report criteria, recommendations are made to strengthen requirement for characterizing problem formulation, dose response and uncertainty analysis. Finally, for risk management decision-making, we recommend consideration for adopting multi-criteria decision analysis and evidence map development. This project summarized the risk assessment criteria of various countries, including the European Union, the United States, and Canada. The description of each criteria, such as the scope, problem formulation, toxicity, dose-response assessment, uncertainty analysis, and the presentation of information were investigated. In comparison, Taiwan's risk assessment guidance lacks the emphasis on the characterization of the exposure scenario, mode of action and the use of benchmark dose methods.
In the process of managing chemical substances, it is often necessary to make decisions without complete information. However, the difficulty of decision-making is not necessarily due to the lack of information, but from the lack of clear definition of decision goals and benchmarks. The uncertainty of the decision-making benchmark comes from the difficulty of its definition. In the process, all aspects of the stakeholders must be considered. It often takes a long time to communicate to reach a consensus. To adequately consider... ， 欄位Project Year的內容是2020 ， 欄位Organizer的內容是Toxic and Chemical Substances Bureau ， 欄位Executive Unit的內容是國立臺灣大學 ， 欄位Reporting download URL的內容是https://epq.epa.gov.tw/ProjectDoc/FileDownload?fid=235117&proj_id=1091917094&doc_kind=1 ， 欄位Publish Date的內容是20210101 。
Project Title
The Development of Decision-making Tool for Chemical Management Based on Risk Analysis: A Pilot Study
Project Subject
In recent years, several incidents of improper use of chemical substances have occurred in Taiwan, causing harm to the environment and the public. In order to more effectively control the source, in 2016, the Toxic and Chemical Substances Bureau of the Environmental Protection Administration of the Executive Yuan was established to strengthen the control, management and supervision of hazardous chemicals for the safeguard of people's health. This project consolidates the classification and assessment frameworks of chemical substances in the European Union, the United States and Canada to discuss the risk-assessment-based classification methods of chemical substances, specifically focusing on their regulatory framework, evaluation and screening process, and use of tools and selection criteria. In addition, the current international trend of advancements in the process of chemical screening are also discussed. The management and evaluation of chemical substances has gradually begun to transform from evaluating single substances to a grouping approach where chemical substances are first classified into groups with similar characteristics, and then evaluating the same class of substances at the same time. Among the many classification schemes, classification based on the chemical’s mode of action is gradually being emphasized, not only for carcinogens, but also non-carcinogenic effects, endocrine effects and ecological assessments. The risk assessment process relies heavily on relevant toxicological information, especially in the steps of hazard identification and dose-response assessment, which make use of data collected from animal experiments. Research has begun to establish methods for data quality assessments and the use of non-experimental toxicological data, including high-throughput screening, computational toxicology, in-silico methods, and integrated testing strategy in risk assessment in hope to replace traditional in-vitro and in-vivo approach. Based on current international trends of chemical substance management framework, this project analyzes the definition of the class 4 toxic chemical substances and concerned chemical substances under the current regulatory framework. The feasibility of distinguishing the two classes of chemicals by their mode of action and human relevance is discussed. Recommendations are made for planning future development and applications of automated chemical screening tools based on existing data analysis tools and Quantitative Structure Activity Relationship (QSAR) models. For risk assessment report criteria, recommendations are made to strengthen requirement for characterizing problem formulation, dose response and uncertainty analysis. Finally, for risk management decision-making, we recommend consideration for adopting multi-criteria decision analysis and evidence map development. This project summarized the risk assessment criteria of various countries, including the European Union, the United States, and Canada. The description of each criteria, such as the scope, problem formulation, toxicity, dose-response assessment, uncertainty analysis, and the presentation of information were investigated. In comparison, Taiwan's risk assessment guidance lacks the emphasis on the characterization of the exposure scenario, mode of action and the use of benchmark dose methods. In the process of managing chemical substances, it is often necessary to make decisions without complete information. However, the difficulty of decision-making is not necessarily due to the lack of information, but from the lack of clear definition of decision goals and benchmarks. The uncertainty of the decision-making benchmark comes from the difficulty of its definition. In the process, all aspects of the stakeholders must be considered. It often takes a long time to communicate to reach a consensus. To adequately consider...
Project Year
2020
Organizer
Toxic and Chemical Substances Bureau
Executive Unit
國立臺灣大學
Reporting download URL
https://epq.epa.gov.tw/ProjectDoc/FileDownload?fid=235117&proj_id=1091917094&doc_kind=1
Publish Date
20210101
「The Development of Decision-making Tool for Chemical Management 」所屬的資料集：「EPQSummary_ChemicalSubstanceManagement」的其他資料
Project Title：
The Integrated Plan for Toxic and Chemical Substances Disater Prevention and Response (Phase I)
Project Subject：
This study collected the toxic chemical substances accident prevention and response mechanism and ru
Project Year：
2018
Organizer：
Toxic and Chemical Substances Bureau
Project Title：
"Project for information integration and knowledge application of environmental risk from toxic and
Project Subject：
"This project has summarized the comprehensive management structures from 6 different nations includ
Project Year：
2017
Organizer：
"Toxic and Chemical Substances Bureau"
Project Title：
Project Subject：
This project is to monitor from source to destination with real-time tracking systems Global Positio
Project Year：
2012
Organizer：
Department of Environmental Sanitation ＆amp; Toxic Substance Management
Project Title：
Project Subject：
The plan had been singed in 21, Apr, 2009. It was executed for 8 1/3 months in 21, Apr to 31, Dec. T
Project Year：
2009
Organizer：
Environmental Protection Bureau, Chiayi City
Project Title：
The Study of Low Frequency Noise Control Criteria and Measures
Project Subject：
This study measured the noise from several construction sites and tried to establish the criteria of
Project Year：
2006
Organizer：
Department of Air Quality Protection ＆amp; Noise Control
Project Title：
"Conference on the Risk Management and Communication of Emerging Contaminants in Sites of H
Project Subject：
"The project aims to thoroughly investigate sites of high potential occurrence of emerging contamina
Project Year：
2018
Organizer：
"Toxic and Chemical Substances Bureau"
Project Title：
The Development of Effective Collection and the most Suitable Collection and Recycling Schemes of Wa
Project Subject：
(1)Due to the various conditions of the 5 domestic waste battery disposing facilities, the surveying
Project Year：
2006
Organizer：
Recycling Fund Management Board
Project Title：
"The Management of Persistent Organic Pollutants and Promotion of Toxic Substance Release Calculatio
Project Subject：
"The achievements made in this project are summarized as follows: 1) The latest information on the S
Project Year：
2016
Organizer：
"Department of Environmental Sanitation ＆amp; Toxic Substance Management"
Project Title：
Advance Stationary Air Pollution Control Strategy and the Certification for Auditor Program
Project Subject：
In order to strengthen and put the stationary sources management into effect, this project divided i
Project Year：
2013
Organizer：
Department of Air Quality Protection ＆amp; Noise Control
Project Title：
Project of the Real-time Monitoring for Environmental Pollution Response in Yunlin County
Project Subject：
This project on purpose to improve effectiveness of disaster prevention and response as well as prep
Project Year：
2015
Organizer：
Environmental Protection Bureau Yunlin County
Project Title：
Membrane module develop in recovering volatile organic compounds
Project Subject：
The exhaust gas of petrifaction industry contain volatile organic compounds(VOCs),it is not only hur
Project Year：
2004
Organizer：
Office of Sustainable Development
Project Title：
Project on Rescue, Prevention, and Guidance of Toxic Chemical Hazards for Taipei City, Academic Year
Project Subject：
待補
Project Year：
2021
Organizer：
Department of Environmental Protection, Taipei City Government
Project Title：
The politic, economic and legal analysis on compliance strategic after Kyoto- part II
Project Subject：
This project includes three parts: first, the discussion and analysis of the key elements after Kyot
Project Year：
2007
Organizer：
Department of Air Quality Protection ＆amp; Noise Control
Project Title：
"Promoting professional and technical service project of prevention and preparedness at emvironmenta
Project Subject：
"The dedicated environmental accident consulting and monitoring center has five groups focusing on p
Project Year：
2015
Organizer：
"Department of Environmental Sanitation ＆amp; Toxic Substance Management"
Project Title：
The Inspection and Certification Third Party on Due Recycled Waste (Waste Lead Acid Batteries)
Project Subject：
For the auditing and certification of waste lead batteries recycling facilities, the main tasks incl
Project Year：
2011
Organizer：
Recycling Fund Management Board
Project Title：
"The Excellence of Toxic and Concerned chemical substance Operation Awards and Promotion Plan"
Project Subject：
"The purpose of this plan is promoting Green chemistry, encouraging innovative research and developm
Project Year：
2020
Organizer：
"Toxic and Chemical Substances Bureau"
Project Title：
Study on the Reduction Verification Mechanism and Standardization of Global Warming Gases
Project Subject：
The items of the mass plan framework of GHG emission reduction verification program and standardizat
Project Year：
2003
Organizer：
Department of Air Quality Protection ＆amp; Noise Control
Project Title：
"Strengthening Toxic Chemicals Flowing Management and information system Project"
Project Subject：
"There are four major aspects in the implementation of this year’s Plan: System planning: The projec
Project Year：
2016
Organizer：
"Department of Environmental Sanitation ＆amp; Toxic Substance Management"
Project Title：
Evaluation of air-cleaning efficiency and Emissior rate of biogenic volatile organic compounds by tr
Project Subject：
This project is to evaluate the air-cleaning efficiency of common tree species in Taiwan and to meas
Project Year：
2003
Organizer：
Department of Air Quality Protection ＆amp; Noise Control
Project Title：
Project of inspection and certification on the recycling waste vechicle(Northern district of Taiwan)
Project Subject：
Since 1997, EPA has launched “public participation feed-back recycling four-in-one project”, which i
Project Year：
2004
Organizer：
Recycling Fund Management Board
Project Title：
"Waste Vehicles Reducing Analysis and Shredding Plants Supervising Project."
Project Subject：
""
Project Year：
2014
Organizer：
"Recycling Fund Management Board"
Project Title：
Final report for implement of the new model certification,conformity of production and the recall re
Project Subject：
According to the records from January 2004 to October 2004, there were 349 certificates issued this
Project Year：
2004
Organizer：
Department of Air Quality Protection ＆amp; Noise Control
Project Title：
"Surveying and inspecting project for post-market chemicals, 2020"
Project Subject：
"The principal work of this project could be divided by three parts, including surveying and inspect
Project Year：
2020
Organizer：
"Toxic and Chemical Substances Bureau"
Project Title：
Audit, Evaluate of Chassis Dynamometer Smoke Test(CDST) station in counties and cities.
Project Subject：
To control air pollution of in-used diesel vehicle effectively, according to the 40th , 41st and 42n
Project Year：
2005
Organizer：
Department of Air Quality Protection ＆amp; Noise Control
Project Title：
ODS Reduction Management Implementation Method and Alternative Technologies to the Montreal Protocol
Project Subject：
The 1987 Montreal Protocol on Substances that Deplete the Ozone Layer (a protocol to the Vienna Conv
Project Year：
2010
Organizer：
Department of Air Quality Protection ＆amp; Noise Control
Project Title：
Project for Stationary Source Integrated Managememt System Planning, Permit System Promotion, Develo
Project Subject：
This project includes 4 major goals：1. Integrate emission management and implement systems. 2. Conso
Project Year：
2008
Organizer：
Department of Air Quality Protection ＆amp; Noise Control
Project Title：
Analytical method establishment of toxic and environmrnt sanitation prohibited substances
Project Subject：
The main purpose of this project is to develop methods and verification in single laboratory for 47
Project Year：
2011
Organizer：
Project Title：
Investigation, Analysis and Application for the Regenerated Product Market of Announced Recycled Was
Project Subject：
The results of investigation showed that by analyzing the components of regenerated wastes, the iron
Project Year：
2005
Organizer：
Recycling Fund Management Board
Project Title：
Surveying and inspecting project for post-market chemicals, 2019
Project Subject：
This project concentrates on (A) surveying and inspecting for post-market chemicals, (B) inspecting
Project Year：
2019
Organizer：
Toxic and Chemical Substances Bureau
Project Title：
"Study and Formulation of Chemicals Management Regulation and its Supplementary Measures Planning Pr
Project Subject：
"Chemical substances safety management is one of the development indicators for advanced countries.
Project Year：
2017
Organizer：
"Toxic and Chemical Substances Bureau"
行政院環境保護署 的其他資料集
環保專案摘要資料_環境教育
不定期更新更新,235陳先生 | 02-2311-7722#2386 | 2023-07-30 01:01:58
行政院環境保護署非甲烷碳氫化合物(NMHC)監測小時值(每小時提供)
每1時更新,100陳先生 | 02-2311-7722#2386 | 2023-08-08 00:58:48
行政院環境保護署經過山坡地之環境影響說明書件
每2月更新,226黃先生 | 02-23117722#2748 | 2023-08-05 01:01:01
行政院環境保護署地方環保局環保稽查次數
每月更新更新,120謝小姐 | 02-23117722#2103 | 2022-01-14 01:21:24
行政院環境保護署環保專案摘要資料_環境衛生
不定期更新更新,122陳先生 | 02-2311-7722#2386 | 2023-07-30 01:02:02
行政院環境保護署
歷年毒性化學物質環境流布調查成果手冊
每年更新更新,36陳小姐 | 23257399#55337 | 2022-01-14 01:22:52
行政院環境保護署Environmental Policy Monthly
不更新更新,201楊先生 | (02)23117722#2217,(02)23117722#2216 | 2022-01-15 01:13:03
行政院環境保護署使用中機動車輛噪音檢驗之場所表
不定期更新更新,38謝先生 | 02-23712121#6403 | 2023-08-07 01:02:18
行政院環境保護署環境影響評估報告書環境敏感區位調查表
每2月更新,148黃先生 | 02-23117722#2748 | 2023-08-05 01:00:55
行政院環境保護署大甲媽祖遶境即時空品監測成果(感測器#3)
不定期更新更新,202陳先生 | 02-2311-7722#2341 | 2022-01-14 01:02:38
行政院環境保護署
水肥清運處理狀況
每1月更新,146余小姐 | 04-22521718#53508 | 2023-08-07 01:02:10
行政院環境保護署基隆市重要環保統計資料
每月更新更新,128謝小姐 | 02-23117722#2103 | 2022-01-14 01:21:45
行政院環境保護署固定污染源戴奧辛、重金屬（鉛、鎘、汞）及氯化氫排放檢測資料
每季更新更新,272江先生 | 02-23117722#6201 | 2022-01-15 01:12:33
行政院環境保護署病媒防治業許可執照資料
每3月更新,114薛先生 | 02-2325-7399#55413 | 2023-07-27 01:02:57
行政院環境保護署全國年度例行性計畫成果統計表（詳情）
不定期更新更新,159賴小姐 | 02-2383-2389#8102 | 2022-01-15 01:12:15
行政院環境保護署
環境影響評估報告書附表五：廢棄物、毒化物
每2月更新,35黃先生 | 02-23117722#2748 | 2023-08-05 01:00:51
行政院環境保護署應回收廢棄物(廢照明光源類)回收量資料
每年更新更新,55廖小姐 | 02-2370-5888#3103 | 2022-01-14 01:24:39
行政院環境保護署共通性事業廢棄物再利用機構資料
每年更新更新,171李小姐 | 02-2311-7722#2633 | 2022-01-14 01:24:44
行政院環境保護署環境教育設施場所認證資料
每月更新更新,115蘇小姐 | 03-4020789#628 | 2022-01-15 01:11:14
行政院環境保護署重點事業廢棄物-有害性集塵灰之處理方式
每月更新更新,163陳先生 | 02-2311-7722#2682 | 2022-01-14 01:24:12
行政院環境保護署
環保標章認證實驗室資料
每1月更新,45黃先生 | 02-23117722#2932 | 2023-07-27 01:01:44
行政院環境保護署行政院環境保護署法定預算
每1年更新,59鄭小姐 | 02-23117722#2156 | 2023-08-09 01:05:49
行政院環境保護署垃圾處理場(廠)統計
每半年更新更新,38掩先生 | (04)2252-1718#53513,#53518,#53522 | 2022-01-14 01:22:10
行政院環境保護署公害陳情上半年度統計分析報告
每8月更新,46許小姐 | 04-22521718#58709 | 2023-08-09 01:04:44
行政院環境保護署公民營廢棄物乙級處理機構許可資料
每1月更新,136盧小姐 | 02-2311-7722#2651 | 2023-07-28 11:35:17
行政院環境保護署
0800資源回收免費專線-查詢事業廢棄物統計
每年更新更新,48莊先生 | 02-23705888#3108 | 2022-01-14 01:24:31
行政院環境保護署訴願決定書
每6月更新,41李先生 | 02-2311-7722#2962 | 2023-07-30 01:05:32
行政院環境保護署焚化廠空污監測資料
每月更新更新,137吳先生 | 04-22521718#53526 | 2022-01-15 01:15:31
行政院環境保護署噪音陳情管道
不定期更新更新,41王先生 | 02-23712121#6401 | 2022-01-14 01:18:43
行政院環境保護署金門縣重要環保統計資料
每月更新更新,115謝小姐 | 02-23117722#2103 | 2022-01-14 01:21:48
行政院環境保護署